Talk:Deinococcus radiodurans

Wiki Education Foundation-supported course assignment[edit]

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Ana Gallego Cortés.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 19:14, 16 January 2022 (UTC)[reply]

Heat resistance[edit]

Where's the evidence that it is resistant to heat? I've read that it is resistant to cold but not to heat.

I see no evidence that it is, nor is there anything in reference no. 6 that indicates this. The sentence by the below poster is not found in that article. We use heat to kill it. Other species of Deinococcus *are* thermophilic but not this one. —Preceding unsigned comment added by 130.39.115.49 (talk) 22:12, 27 February 2008 (UTC)[reply]

I have removed "heat" from the first line. Please source your evidence if you revert. —Preceding unsigned comment added by 130.39.115.49 (talk) 22:19, 27 February 2008 (UTC)[reply]

The link in reference no. 5 is incorrect.

I think that you meant the PMID in reference no. 6, which I have just fixed. The organism is resistant to all forms of stress, including dessication and heat. Reference no. 1 has information on this. I had to fix the PMID for that reference as well. --Ben Best 00:23, 15 October 2006 (UTC)[reply]

I'll have to contact someone to find the links to relevant research but IIRC the heat resistance of D. radiodurans was evidenced by its reaction to dessication. They were able to heat it to a high degree evaporating most of the liquid (dessication) and when it was re-introduced to fluids it re-hydrated with very little/no genetic disruption. This is not true of most single cell structures. For example blood has to be kept fluid (and cold) and cannot be stored in a powdered form.—Preceding unsigned comment added by JMBattista (talk • contribs) 05:22, 27 March 2007 (UTC)[reply]

Martian origins?[edit]

Should there be any mention about potentially Martian origins? There's a BBC article about that here: http://news.bbc.co.uk/2/hi/science/nature/6191197.stm

Maybe, but it's uncertain. I do agree that most likely panspermia happened between Earth, Mars, and some other planet/moon.137.118.105.152 (talk) 20:54, 20 February 2019 (UTC)[reply]

Removed statement[edit]

I have removed the statement: " Certain scientists are trying to implement genes into D. radiodurans that will cause its protein to disable metals with which they come into contact. In doing so, this bacterium may be able to metabolize heavy metals such as plutonium, uranium, and other radioactive metals into harmless matter. ^{[dubious – discuss]}" This cannot be correct. Radioactive materials do not lose their radioactivity through chemical processes.

Actually what happens is the radioactive metal is reduced or is caused to form a compound. The resulting product, while still radioactive, becomes insoluble and easier to sequester. So it's true that the metals are metabolized, but false that they become harmless. Ask google about nuclear bioremediation for some links.Viracocha (talk) 22:18, 25 March 2008 (UTC)[reply]

DNA repair in other species[edit]

In several locations within this article, the DNA repair capability of D. radiodurans is described as "unique". This is not the case. The process of repairing a DSB is common, what is unique however, is the accuracy (lack of errors) of the process in D. radiodurans compared to other prokaryotes, such as E. coli. See the below paper. The radioresistance of D. radiodurans is more likely attributable to the protection of its proteome by ROS scavenging. (which protects the DNA repair machinery, making it less error prone than in E. coli). --Appelflappenn (talk) 15:00, 29 April 2021 (UTC) ^[1][reply]

I've removed this statement:

Some have speculated that mechanisms of DNA repair used by D. radiodurans could be incorporated into the genome of higher species as a means of rejuvenation.^[2]

I don't know of anyone who suggests that possibility, and the referenced article certainly doesn't. The special repair mechanism would require multiple copies of each chromosome to be stacked on top of each other, which I can't imagine would be feasible in eukaryotes due to the more complicated chromosome structure. But feel free to add it back if you find a better reference.Viracocha (talk) 22:18, 25 March 2008 (UTC)[reply]

References

^ Krisko, Anita; Radman, Miroslav (10 August 2010). "Protein damage and death by radiation in Escherichia coli and Deinococcus radiodurans". Proceedings of the National Academy of Sciences. 107 (32): 14373–14377. doi:10.1073/pnas.1009312107.
^ Zahradka K, Slade D, Bailone A, Sommer S, Averbeck D, Petranovic M, Lindner AB, Radman M (2006). "Reassembly of shattered chromosomes in Deinococcus radiodurans" (PDF). Nature. 443 (7111): 569–573. PMID 17006450.{{cite journal}}: CS1 maint: multiple names: authors list (link)

Info on bacterium?[edit]

Where does it live, how big is it, what does it do all day? AxelBoldt (talk) 23:47, 26 January 2008 (UTC)[reply]

And, what -does- kill it? high enough heat to decompose the organic molecules has to at some point, but anything short of holding it in a flame? —Preceding unsigned comment added by 68.116.67.106 (talk) 05:06, 9 February 2008 (UTC)[reply]

Just out of curiosity, is D. radiodurans potentially harmful to humans or any other animals? —Preceding unsigned comment added by 172.192.149.119 (talk) 22:37, 24 March 2008 (UTC)[reply]

No, there aren't any known pathogenic extremophiles. Viracocha (talk) 22:18, 25 March 2008 (UTC)[reply]

Transliteration of the name[edit]

Previous version: 'terrifying berry that withstands radiation'

The Greek deinos can mean terrifying or marvellous, as in deinos legein (marvellous in speaking) but marvellous is more likely for the bacterium, we marvel at it's resistance rather than being scared of it.

Aksel89 (talk) 08:16, 2 November 2008 (UTC)[reply]

Please read talk page. δεινός doesn't exclusively mean terrifying.

See here for translations of deinos which include "awesome" and here for the Greek adjective "terrible". Aksel89 (talk) 06:40, 27 April 2009 (UTC)[reply]

Viability for amount of grays? Not for amount of gray per day?[edit]

D. radiodurans is capable of withstanding an instantaneous dose of up to 5,000 Gy with no loss of viability

Point of improvement: Does viability not mean that it can survive under constant irradiation? So shouldn't the unit be how much gray per time unit? (Also, viability does not get me a link to an article) 88.159.73.156 (talk) 22:42, 4 February 2009 (UTC)[reply]

"consuming" heavy metals[edit]

Deinococcus has been genetically engineered for use in bioremediation to consume and digest solvents and heavy metals, even in a highly radioactive site.

Could a knowledgeable editor rephrase this so it doesn't sound like it's able to actually destroy heavy metal atoms? Comet Tuttle (talk) 19:53, 26 October 2009 (UTC)[reply]

Evolution[edit]

An article about a bacterial species can never be complete without a description or an account of its evolution. How does DR's genome contribute to its survival and how did it evolve? Wayne Hardman (talk) 01:25, 28 December 2009 (UTC)[reply]

Laboratory simulation of interplanetary ultraviolet radiation[edit]

Laboratory simulation of interplanetary ultraviolet radiation (broadspectrum) and its effects on Deinococcus radiodurans: [1]. BatteryIncluded (talk) 22:07, 23 September 2012 (UTC)[reply]

Deinococcus radiodurans has the unique ability to repair DNA[edit]

Deinococcus Radiodurans is a species of bacteria capable of repairing DNA and in the absence of this gene, the bacteria can still repair DNA damage, but will not grow. Deinococcus radiodurans can withstand an acute ino radiation of 5,000 Gy. Lý Lượng Tử (talk) 06:32, 1 May 2021 (UTC)[reply]

[1] Krisko, Anita; Radman, Miroslav (10 August 2010). "Protein damage and death by radiation in Escherichia coli and Deinococcus radiodurans". Proceedings of the National Academy of Sciences. 107 (32): 14373–14377. doi:10.1073/pnas.1009312107.

[MRadman-2] Zahradka K, Slade D, Bailone A, Sommer S, Averbeck D, Petranovic M, Lindner AB, Radman M (2006). "Reassembly of shattered chromosomes in Deinococcus radiodurans" (PDF). Nature. 443 (7111): 569–573. PMID 17006450.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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