Talk:Growth dysplasia

Is the wombat comment true or is someone being silly? The Singing Badger 18:36, 2 Apr 2005 (UTC)

disputed topics

• wrong definition 'defect that causes animals to grow too large to support themselves.'. Any morbidly obese patient is too large to support himself, and the cases of gigantism in humans hardly if ever resulted in lack of support.

Anonymous wrote: FYI, most people defined as "morbidly obese" are NOT too large to support themselves because the range of definition is too broad. There are, as yet, NO scientific definitions of "overweight" or "obese" and, thus, there is no scientific definition of "morbidly obese". Caution: There are several *common* and PURELY ARBITRARY definitions of obesity, often relying arbitrarily on mathematical calculations of height and weight (e.g., body mass index), but these are NOT scientifc. There has been no inductive *or* deductive research conducted which has produced any scientific definition of "obesity."

Yep. There is no such thing like obesity, no obesity research and ppl weighting 400 pounds support themselves amply while climbing vertical walls with flying pigs circling above their heads. "Morbidly obese" is a medical term so is 'fever' even if borders for these were set arbitrary. Darked 12:35, 11 July 2006 (UTC)

• terms growth & dysplasia are used predominantly for describing cancerous growth (source Pubmed

• searching Pubmed with "growth dysplasia" gives four articles, one ( "From genotype to phenotype: the differential expression of FGF, FGFR, and TGFbeta genes characterizes human cranioskeletal development and reflects clinical presentation in FGFR syndromes" Plast Reconstr Surg. 2001 Dec;108(7):2026-39; discussion 2040-6.) stating

Maximal FGFR expression in the skull base proposes a pivotal role for syndromic growth dysplasia at this site.

• the more appropriate name should be Overgrowth Syndrome

http://www.endotext.org/pediatrics/pediatrics1/pediatrics1b/ch01s05.html

• there is no shred of evidence of wombats having any problems with growth (google, a9),neither there is any info about hybrids between wombat species
• the origin of the above statements is from User:66.210.57.9 who seems to be a highschool prankster

Unless some medical or veterinary expert can confirm that indeed "growth dysplasia" as described here makes sense I suggest deleting the whole article and start Overgrowth Syndrome to replace it. Darked 01:00, 6 June 2006 (UTC)

I've created a new article (hybrid growth disorders) to replace this article, based on a Nature paper I found studying abnormal growth in hybrid mice. Because they use the term "growth dysplasia" sparingly, I've kept a bit about the terminology, and am making this article a redirect rather than replacing it. I removed the comments about inbreeding, because I could not find any peer-reviewed research to support this. I also took out the section about how liger growth dysplasia would "theoretically" work, because again I cannot find any actual study which was ever done that indicates this is the actual mechanism. From what I understand, the genes, and types of mechanisms responsible for hybrid growth disorders can vary greatly from species to species.